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. 2017 Apr 25;1(6):751–761. doi: 10.1210/js.2017-00189

Table 4.

Relationship Between Neonatal Dysthyroidism and Predictor Variable (Maternal or Neonatal TRAb Level)

Predictor Variable Optimal Cutoff, IU/L Sensitivity, % Specificity,% PPV, % NPV, % Correctly Classified % AUC
All women (n = 417)
 Maternal MaxTRAb 5.9 100 (100–100) 82 (78–86) 26 (22–30) 100 (100–100) 83 0.97 (0.95–0.99)
 Neonatal TRAb, D0–D5 6.8 100 (100–100) 94 (92–96) 50 (45–55) 100 (100–100) 92 0.98 (0.97–0.99)
Receiving ATDs during  pregnancy
 Yes (n = 145; 35.0%)
  Maternal MaxTRAb 5.9 100 (100–100) 61 (53–69) 29 (22–36) 100 (100–100) 66 0.93 (0.87–0.98)
  Neonatal TRAb, D0–D5 6.8 100 (100–100) 89 (84–94) 59 (51–67) 100 (100–100) 90 0.97 (0.94–0.99)
 No (n = 272; 65.0%)
  Maternal MaxTRAb 5.9 100 (100–100) 92 (89–95) 19 (15–23) 100 (100–100) 92 0.99 (0.97–1.0)
  Neonatal TRAb, D0–D5 6.8 100 (100–100) 96 (94–98) 31 (25–37) 100 (100–100) 96 0.99 (0.99–1.0)

Data in parentheses are 95% confidence intervals.

Abbreviation: MaxTRAb, maximum TRAb.