Table 1.

Baseline characteristics of 13 incident end-stage renal disease (ESRD) patients initiated on twice-weekly hemodialysis schedules.

Patient	Age	Sex	Race/ Ethnicity	Cause of ESRD	Diabetes (Y/N)	HTN (Y/N)	CVD (Y/N)	Duration on twice- weekly HD (months)	Transition to thrice- weekly HD (Y/N)	Reason for transition from twice- weekly to thrice-weekly HD
Patient 1	71	F	Hispanic	Diabetic nephropathy	Y	Y	Y	15.5	Y	IDWG and fluid overload
Patient 2	43	F	Non-Hispanic White	Diabetic nephropathy	Y	Y	N	11	Y	IDWG and new onset HFrEF
Patient 3	59	M	Non-Hispanic White	Diabetic nephropathy	Y	Y	N	6	Y	IDWG and fluid overload
Patient 4	70	M	Hispanic	Obstructive nephropathy	Y	Y	Y	9	Y	IDWG
Patient 5	20	M	Hispanic	Membranoproliferative glomerulonephritis	N	N	N	5	Y	Adequacy (hyperkalemia)
Patient 6	50	F	Hispanic	Hypertension, NSAID use	N	Y	N	5	Y	Adequacy (acidosis, hyperkalemia, hyperphosphatemia)
Patient 7	68	F	Asian	Diabetic nephropathy	Y	Y	Y	4	Y	Adequacy (hyperkalemia, acidosis, low clearance)
Patient 8	50	M	Asian	Chronic interstitial nephritis	N	Y	N	6	Y	Adequacy
Patient 9	73	M	Asian	Hypertension/Ischemic nephropathy	Y	Y	Y	12	N	N/A
Patient 10	66	F	Hispanic	Reduced nephron mass (partial nephrectomy), hypertension, diabetic nephropathy	Y	Y	N	20	N	N/A
Patient 11	31	M	Hispanic	Tuberous sclerosis	N	N	N	8	N	N/A
Patient 12	59	M	Hispanic	IgA nephropathy & Focal segmental glomerulosclerosis	N	Y	N	7	N	N/A
Patient 13	25	M	Non-Hispanic White	Congenital renal dysplasia/solitary kidney	N	Y	N	3.5	N	N/A

Abbreviations: M: male; F: female; Y: yes; N: no; HTN: hypertension; CVD: cardiovascular disease; HD: hemodialysis; IDWG: interdialytic weight gain; HFrEF: heart failure with reduced ejection fraction; URR: urea reduction ratio