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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Lancet Respir Med. 2017 Sep 21;5(11):857–868. doi: 10.1016/S2213-2600(17)30349-1

Figure 1. Study design.

Figure 1

The outline summarizes the (a) time to event and (b) time course analysis design for this study including the cohorts, blood compartments, experiments and statistical methods used in each independent cohort and in the pooled data analysis. PBMC: Peripheral blood mononuclear cells. BWH-HMS: Brigham and Women’s Hospital-Harvard Medical School. Dates of enrollment for each cohort are included in figure 1a. For figure 1b, time is presented in years (average and range, in parenthesis).