Figure 3. Conditioned and unconditioned fear-related behaviors were reduced in SynAsic1a KO mice.
A) Compared to their respective control groups, both global Asic1a−/− mice and neuron-specific SynAsic1a KO mice exhibited reduced freezing during acquisition, cued testing, and context testing (n = 10, 10, 14, 17). B) CO2-evoked freezing was reduced in both global Asic1a−/− mice and SynAsic1a KO mice (n = 11, 10, 14, 17). C) TMT-evoked freezing was reduced in both global Asic1a−/− mice and SynAsic1a KO mice (n = 10, 10, 14, 16).