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. Author manuscript; available in PMC: 2017 Nov 9.
Published in final edited form as: Prog Neurobiol. 2016 Apr 14;141:45–60. doi: 10.1016/j.pneurobio.2016.04.005

Table 3.

Neurorepair based on cell therapy for WMI under investigation

Source of stem cells Potential mechanisms
ADMSC Immunomodulation, anti-apoptotic, promotion of trophic factor production, stimulation of axonal growth and oligodendrogenesis,
HUSBC Anti-inflammatory, enhancement of vascular remodeling
BMSC Stimulation of axonal growth and oligodendrogenesis
OPCs Stimulation of BDNF expression, enhancement of neurogenesis, anti-apoptotic and remyelinated the damaged axon