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. 2017 Sep 22;139(40):14192–14197. doi: 10.1021/jacs.7b07352

Figure 4.

Figure 4

Competitive ABPP experiment of HEK293T cells overexpressing GBA2 or GBA3 (and expressing endogenous GBA) treated with compounds 912 at various final concentrations prior to cell lysis and ABPP profiling of remaining enzyme activity.