. 2017 Aug 21;139(36):12550–12558. doi: 10.1021/jacs.7b05937

Table 1. Properties of Ligands L₀–L₅, Measured Log P_oct Values for the Corresponding ⁶⁴Cu-Radiolabeled Complexes, and Aβ Fibril-Binding Affinity K_i Values for BFCs and their Cu Complexes (NA = Not Applicable).

ligand	MW (g mol^–1)	log P_oct	K_iL_n (nM)	K_i Cu-L_n (nM)
L₀	384.4	–1.09 ± 0.16	NA	NA
L₁	426.6	0.97 ± 0.12	170 ± 50	765 ± 30
L₂	509.6	0.72 ± 0.08	30 ± 10	275 ± 20
L₃	523.7	0.64 ± 0.11	40 ± 10	325 ± 25
L₄	567.9	0.82 ± 0.05	320 ± 40	2350 ± 250
L₅	779.0	0.92 ± 0.07	580 ± 150	142 ± 55

Table 1. Properties of Ligands L0–L5, Measured Log Poct Values for the Corresponding 64Cu-Radiolabeled Complexes, and Aβ Fibril-Binding Affinity Ki Values for BFCs and their Cu Complexes (NA = Not Applicable).