Table 3.

Principles for decision-making

Overarching principles

Clinically driven

• Patient participation and autonomy will be fostered.

• Genome data will be analysed according to clinical indication.

Collaborative

• Genomic data will be shared for clinical and research use according to existing regulations for health records and ethical standards.

• Common systems and standards apply where they will facilitate access to and (re-) use of genomic information by multiple partners throughout the patient’s lifetime and across the research-translation continuum.

• Each member remains responsible for business decisions about the services it provides and the resourcing and quality assurance of those services.

• Each hospital remains responsible for procurement of genomic testing for their patients, subject to the provider meeting the shared standards.

Sustainable

• Decisions during development will be ‘user-focussed’—where those users are variously patients, clinicians, researchers and diagnostic laboratories—and evidence-based.

• Systems will be designed for optimal (financial) sustainability, scalability, incorporation of future -omics advances and future inclusion of organisations outside the founding members.