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. 2017 Jul 10;2:23. doi: 10.1038/s41525-017-0024-5

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Skeletal features of Roifman syndrome in patients 1 and 2. a Pelvic X-ray of patient 1 featuring flattening of the humoral heads and shortening of the femoral necks, representing early stages of spondyloepiphyseal skeletal dysplasia. b Lateral spine X-ray of patient 1 featuring anterior vertebral notching of the lower thoracic vertebrae, and loss of lumbar lordosis. c Pelvic X-ray of patient 2 featuring bilateral small, flattened and slightly broadened femoral heads. d Lateral spine X-ray of patient 2 featuring loss of lumbar lordosis.