Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 8;7:15035. doi: 10.1038/s41598-017-14778-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Evaluation of the 20q12 locus (a) Regional association plot derived from the GWAS result of imputation analysis for idiopathic osteonecrosis of the femoral head. The region surrounded by distinct peaks of recombination rate (yellow box) was identified as a disease susceptibility locus. Only LINC01370 was within this locus. The color intensity reflected the extent of linkage disequilibrium index (r ²) with rs6028718 (in purple). Estimated recombination rates from the hg19/1000 Genomes Project Nov 2014 East Asian reference were shown as light-blue lines. (b) The topologically associated domain around the 20q12 locus (green box). Aside from LINC01370, this domain contained DHX35 (DEAH-box helicase 35) and MAFB (MAF bZIP transcription factor B).