Table 1.
Phenotype | Case | Control1 | Genotyped SNP | ||||
---|---|---|---|---|---|---|---|
Sample | Male | Female | Sample | Male | Female | ||
IONFH | 1,547 | 777 | 770 | 59,103 | 32,135 | 26,968 | 525,308 |
Stratified analysis based on risk factors 2 | |||||||
Steroid-associated | 1,058 | 386 | 672 | 59,103 | 32,135 | 26,968 | 525,264 |
Alcohol-associated | 351 | 316 | 35 | 59,103 | 32,135 | 26,968 | 524,775 |
Neither-associated | 132 | 70 | 62 | 59,103 | 32,135 | 26,968 | 523,825 |
Stratified analysis based on alcohol intake 3 | |||||||
Alcohol-associated | 351 | 316 | 35 | 3,647 | 3,349 | 298 | 525,254 |
1Derived from BioBank Japan. 2Six patients could not be classified because sufficient information for classification could not be obtained. 3Controls were matched for alcohol-drinking history (400 ml or more ethanol consumption per week). IONFH: idiopathic osteonecrosis of the femoral head.