Table 1.
Isogenic clone frequencies for each genotype produced from pipeline for Gastric Cancer VUSs PALB2-SNV and PALB2-DEL in HEK293 cells and for Colorectal Cancer Risk SNP rs6983267 in HCT-116 cells.
a. | ||||
PALB2-SNV | WT/WT | WT/Mut | Mut/Mut | Total Clones |
42 | 4 | 2 | 48 | |
87.5% | 8.3% | 4.7% | ||
PALB2-DEL | WT/WT | WT/Mut | Mut/Mut | Total Clones |
50 | 3 | 4 | 57 | |
87.7% | 5.3% | 7.0% | ||
b. | ||||
8q24-SNP Single-Clones | WT/WT | WT/Mut | Mut/Mut | Total Clones |
96 | 5 | 0 | 101 | |
95.0% | 5.0% | 0.0% |