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. 2017 Nov 8;7:15012. doi: 10.1038/s41598-017-15357-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Flow cytometry analysis of ex vivo synaptic binding of 5 μM Aβ oligomers. Representative flow cytometry analysis of the 5 μM Aβ oligomer binding in synaptosomes isolated from (a) parieto-occipital cortex (POCX) (b) frontal cortex (FCX) and (c) hippocampus in NIR light treated and sham treated wild type mice. (d) The results indicate a significant reduction in the percentage of Aβ positive synaptosomes in the three brain regions POCX, FCX and hippocampus of NIR light treated mice (black) compared to sham treated mice (white). (n = 8; per group). Statistical significance was determined by Student’s two tailed t-test analysis. Error bars represent standard deviation. *p < 0.05; ^#p < 0.01.