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. 2017 Nov 8;7:15102. doi: 10.1038/s41598-017-14531-5

Figure 3.

Figure 3

Compilation of individual bubble bursting simulations. (a) In contrast to previous numerical studies (red squares and blue circles), we find that all bubbles produce an overall maximum level of EDR exceeding the generally accepted lethal threshold for CHO cells (hatched region) and that this maximum depends on the level of mesh refinement. (b) The spatial maximum of the EDR varies with time t and reaches a temporal maximum at t ≈ 369 μs for the R = 385 μm air bubble cases circled in part (a). (c) The time at which the maximum EDR is reached, capillary waves have converged at the base of the bubble to create a region of high-curvature that pinches off to form a small bubble. (d) The local features and corresponding EDRmax depend on the level of mesh refinement, as might be expected from the singular dynamics associated with these capillary waves.