Table 2.
MRI acquisition parameters.
Sequence | Parameters |
---|---|
B0 field map | Double echo FLASH sequence (matrix size = 64 × 64; 64 slices; spatial resolution = 3 × 3 × 3 mm3; gap = 1 mm; short TE = 10 ms; long TE = 12.46 ms; TR = 1020 ms) to correct EPI images for distortion in the B0 field (Weiskopf et al., 2006). |
Functional, EPI | Restricted volume, 44 slices (40 in slab with 10% oversampling), FoV read 192 mm, transverse slices tilted 20°, anterior-posterior phase encoding, 12% phase oversampling, 10% slice oversampling, 40 slices per slab, voxel size 1.5 mm isotropic, TR = 78 ms (volume TR = 3432 ms, i.e. 44 slices * 78 ms), TE = 37.3, GRAPPA2 along phase encoding (full set of external reference scans with 144 PE ref. lines, 44 3D ref. lines), 180–185 vol per block depending on duration of block over 4–10 min blocks in total (Lutti et al., 2012). |
Multi-parameter maps | Proton density (PD)-weighted, T1-weighted, and magnetization transfer (MT)-weighted images at 0.8 mm isotropic resolution for each participant using multi-echo 3D FLASH, TR = 25 ms, TE = [2.34, 4.64, 6.94, 9.24, 11.54, 13.84, 16.14, 18.44] ms, FOV read 256 mm, FOV phase 87.5%, slice partial Fourier 6/8, GRAPPA acceleration 2 (Dick et al., 2012, Helms et al., 2008). Flip angle for PD and MT was 6°, for T1 21°. A B1-map was acquired using a 3D SE/STE EPI method to correct for the effects of inhomogeneous radio-frequency excitation on the quantitative maps (Lutti et al., 2012). Total time of acquisition was ∼40 min. |
Diffusion-weighted, whole-brain | Whole-brain 1.5 × 1.5 × 1.5 mm3 resolution diffusion-weighted images with settings similar to the Human Connectome Project (Sotiropoulos et al., 2013, Van Essen et al., 2012). Three shells (b = 900/1800/2700) for both right-left and left-right phase-encoding directions. Each of these 6 scans contained 10 images with no diffusion weighting (b = 0) and 100 directions spread out over a full sphere. We used multiband 3 but no further acceleration. Acquisition time was 10 min 20 s for each of the 6 scans. No phase oversampling, 75 transverse slices, FoV read 192 mm, FoV phase 100%, slice thickness 1.5 mm with 0 distance between slices, TR 5440, TE 130 ms. We additionally acquired two b0 images with identical settings, but phase encoding along anterior-posterior and along posterior-anterior respectively. These additional phase encoding directions were included in estimating distortions along the phase encoding direction. |