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. 2017 Nov 30;15(4):313–319. doi: 10.9758/cpn.2017.15.4.313

Table 1.

Importance of microRNAs subject to this review

MicroRNA Psychiatric disorder Importance
miR-320 Major depression miR-320 family may be important as a peripheral biomarker
Autism miR-320 was dysregulated in lymphoblastoid cell lines of autism patients
miR-106 Major depression miR-106a-5p levels was higher in depressed patients
Schizophrenia miR-106b-5p levels was higher in schizophrenia patients
Attention deficit hyperactivity disorder Lower miR-106b-5p levels were determined in the control group
Autism miR-106-5p showed higher expression in autism
miR-34 Major depression miR-34b-5p and miR-34c-5p levels in peripheral blood leukocytes were closely related to suicide idea and cognitive function
Schizophrenia miR-34 were presented as peripheral biomarkers
Bipolar disorder miR34-a may be critical for bipolar disorder in terms of neurodevelopment
Alzheimer’s disease miR-34a was observed to be decreased in plasma and cerebrospinal fluid according to the control group
miR-223 Major depression miR-223-3p levels were reported to be significantly higher in patients than in controls
Posttraumatic stress disorder miR-223 could be a potential biomarker
miR-107 Amnestic mild cognitive impairment miR107 expressions in plasma had a high capability to distinguish individuals with amnestic mild cognitive impairment from healthy controls
Major depression Positive correlation between N1, P2latency of P300 and miR-107 in depressed patients
miR-134 Mild cognitive impairment miRNA biomarker pairs successfully detected MCI in most of the patients at asymptomatic stage
Bipolar disorder Decreased miR-134 level was directly associated with bipolar disorder