Table 2.
TKV slopes (percent change per year), by image-based classification and treatment group
| Class | Class 1B | Class 1C | Class 1D | Class 1E | Class 2A/2B | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | PLC n = 29 |
TLV n = 64 |
PLC n = 186 |
TLV n = 288 |
PLC n = 150 |
TLV n = 291 |
PLC n = 76 |
TLV n = 144 |
PLC n = 17 |
TLV n = 25 |
| TKV slope (%/yr) | 3.25 | 1.23 | 5.12 | 1.79 | 5.62 | 3.03 | 7.75 | 4.96 | 2.48 | 2.27 |
| 95% CI | 1.50, 5.03 | 0.30, 2.17 | 4.35, 5.90 | 1.26, 2.32 | 4.58, 6.68 | 2.47, 3.59 | 6.16, 9.35 | 4.03, 5.89 | −0.34, 5.39 | 0.11, 4.47 |
| Treatment effect (%/yr) | −2.00 | −3.27 | −2.52 | −2.66 | −0.21 | |||||
| 95% CI | −3.76, −0.27 | −4.03, −2.52 | −3.54, −1.50 | −4.17, −1.16 | −3.05, 2.55 | |||||
| P value | 0.02 | <0.001 | <0.001 | <0.001 | 0.88 | |||||
CI, confidence interval; PLC, placebo treatment group; TKV, total kidney volume.