Table 3.
Prevalence of SAEs associated with corticosteroids in the corticosteroid user group and corticosteroid nonuser group, and median time from initial use of corticosteroids to SAE occurrence
| SAEs | Corticosteroid users, n (%) | Time, median (range) (mo) | Corticosteroid nonusers, n (%) |
|---|---|---|---|
| Diabetes mellitus | 19 (5.1) | 3.5 (0.5–55.4) | 3 (16.7) |
| Severe infection | 18 (4.9) | 3.8 (1.1–14.4) | 10 (55.5) |
| Death | 7 (1.9) | 12.4 (2.3–64.8) | 0 |
| Osteonecrosis of femoral head or bone fracture | 6 (1.6) | 22.4 (1.3–57.2) | 2 (11.1) |
| Cardiocerebral vascular disease | 4 (1.1) | 7.2 (2.0–31.1) | 2 (11.1) |
| Cataract | 3 (0.8) | 11.4 (5.6–17.1) | 0 |
| Gastrointestinal hemorrhage | 1 (0.3) | 3 | 1 (5.6) |
| Total | 58 | 4.9 (0.5–64.8) | 18 |
SAEs, severe adverse effects.