Table 2. Fold-change in expression of pro-fibrotic genes between α7 genotypes and CS versus LPS.
Gene | G* CS/C | E** CS/C | G*/@ LPS/C | E**/@ LPS/C |
---|---|---|---|---|
Col1a1 | 0.91 | 1.92 | 2.75 | 12.20 |
Col1a2 | 1.01 | 2.27 | 1.94 | 10.51 |
Col3a1 | 0.89 | 2.39 | 2.24 | 10.52 |
Col4a1 | 0.67 | 1.20 | 4.87 | 4.78 |
Col4a2 | 0.79 | 1.34 | 5.23 | 5.52 |
Col4a3bp | 0.69 | 1.15 | 2.64 | 1.42 |
Col5a2 | 0.94 | 2.03 | 1.94 | 6.63 |
Col6a1 | 1.30 | 1.86 | 3.41 | 7.47 |
Col6a2 | 1.14 | 1.91 | 2.08 | 7.82 |
Col6a3 | 1.14 | 0.69 | 1.30 | 4.64 |
Col14a1 | 1.02 | 2.90 | 2.00 | 7.26 |
Mmp2 | 1.16 | 2.00 | 3.94 | 7.13 |
Mmp3 | 1.37 | 2.56 | 4.25 | 11.30 |
Mmp8 | 1.18 | 0.74 | 14.31 | 8.01 |
Mmp9 | 1.70 | 0.89 | 8.70 | 5.65 |
Mmp12 | 0.49 | 0.10 | 0.10 | 0.06 |
Mmp15 | 0.64 | 2.11 | 0.76 | 2.28 |
Mmp19 | 0.63 | 0.86 | 1.57 | 1.05 |
Timp2 | 1.47 | 1.05 | 2.68 | 3.73 |
Timp3 | 0.99 | 2.66 | 16.68 | 10.45 |