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. 2017 Sep 21;18(10):806–815. doi: 10.1080/15384047.2017.1373219

Figure 1.

Figure 1.

KLF5 expression in gastric cancer associated fibroblasts and gastric cancer stromal tissues. (A) The dysregulated genes were analyzed by cDNA array used 6 paired CAFs and NFs obtained from patients with gastric cancer. (B) Eight selected genes were analyzed by qRT-PCR in CAFs and NFs derived from gastric cancer patients. Data are shown as fold changes between CAFs and NFs. (C, D) The expression of KLF5 protein in 3 paired CAFs and NFs were measured by Western-blot assay. (E, F) Representative images of KLF5 immunostaining assay in gastric cancer stromal tissues. Kaplan-Meier analysis showed that high level of KLF5 expression in stroma is associated with decreased overall survival (P = 0.04). Data are representative of three independent experiments. *P < 0.05 by t test, **P < 0.01 by t test.