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. 2017 Oct 27;11(10):e0006043. doi: 10.1371/journal.pntd.0006043

Table 1. Included studies with quantitative data on MDA coverage rates.

Intervention Study [reference] Study Design (N)a Country Outcome Measurement Methods Integrated Program?b Coverage related factors discussed?
Combined school- and community-based Oshish 2011 [14] Pre-Postc (325,509) Yemen Drug distributor registers and projected census data No Yes
Gabrielli 2006 [15] Pre-post (3,659,211) Burkina Faso School and drug distributer registers and census data No Yes
Sesay 2014 [16] Pre-Post (2,375,539) Sierra Leone Drug distributors registers and independent survey No No
Dembélé 2012 [17] Pre-post (3,046,078) Mali Drug distributor registers and census data Yes Yes
Leslie 2011 [18] Pre-Post (288,078) Niger Aggregated treatment registers and national annual treatment summary No No
Community-based Hopkins 2002 [19] Pre-post (5,214) Nigeria Not reported Yes No
Anto 2011 [20] Non-randomized control trial (3,520) Ghana Aggregated drug distributor registers Yes Yes
Mwinzi 2012 [21] Pre-post (3,677) Kenya Aggregated distributor registers and household surveys No Yes
Chami 2015 [22] Observational (935) Uganda Drug distributor registers, post-treatment surveys in villages No Yes
School-based Muhumuza 2013a [23] Observational (1,010) Uganda School-based survey of enrolled SAC No Yes
Muhumuza 2013b [24] Pre-post (1,020) Uganda School-based survey of enrolled SAC No Yes
School-based vs. community-based Ndyomugyeni 2003 [25] Non-randomized comparative trial (954) Uganda Household survey Yes Yes
Mafe 2005 [26] Non-randomized comparative trial (3,827) Nigeria Household survey No Yes
Massa 2009 [27, 28] Randomized comparative trial (7,039) Tanzania Drug distributor registers No Yes

a N is overall number of targeted SAC in study

b Programs were considered to be “integrated” if they included distribution of drugs other than PZQ and albendazole or mebendazole, such as ivermectin or DEC for onchocerciasis and filariasis.

c Pre-post indicates outcomes were scored based on pre- and post-intervention surveys of a non-randomized trial to improve participation

d Aggregate coverage rates were reported for adult and SAC, together, in these studies