Fig. 2.

Significant negative correlation between the increased glutamine metabolism and 5-year survival rate across the 11 types of cancer. The X axis represents the level of change in glutamine metabolism, which is the difference between the levels of glutamine metabolism in cancer versus control tissues; the Y axis represents the 5-year survival rate of cancer. The average level of change in glutamine metabolism across three subtypes of the kidney cancer (KICH, KIRC, and KIRP) is used because there are no 5-year survival data for the individual subtypes. BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; COAD, colon adenocarcinoma; HNSC, head and neck squamous cell carcinoma; KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; PRAD, prostate adenocarcinoma; THCA, thyroid carcinoma