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. 2016 Jan 20;3:39–51. doi: 10.1016/j.meteno.2016.01.002

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© 2016 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 5 — Flux distribution maps for S. cerevisiae IME307 (Δpdc1,5,6 Δilv2 MTH1ΔT^coilvBCDN^cokdcA) grown in micro-aerobic cultures (see Table 6), calculated using CellNetAnalyzer. Dashed arrows represent multiple enzyme-catalysed reactions. Numbered boxes represent the modelled metabolic flux through each reaction (expressed in µmol/g biomass/h). Mal/asp: malate/aspartate shuttle, ETC: Electron transport chain, OXPHOS: Oxidative phosphorylation, G-6P: glucose-6-phosphate, G-3P: glyceraldehyde-3-phosphate, DHIV: 2,3-dihydroxyisovalerate, KIV: α-ketoisovalerate.