Table 1.
Patient characteristics according urinary creatinine excretion level
| Characteristics | All CKD patients N = 1287 |
Low UCrE 38% |
Normal UCrE 62% |
|---|---|---|---|
| UCrE in men (mmol/24 h) | 9.4 (7.6−11.4) | 7.5 (6.3−8.5) | 11.0a (9.7−12.4) |
| UCrE in women (mmol/24 h) | 6.9 (5.7−8.4) | 5.2 (4.7−6.1) | 8.0a (6.8−9.2) |
| Demographics | |||
| Age (yr) | 63.1 (51.9−72.4) | 62.5 (51.6−70.4) | 64.2b (52−74.1) |
| Men (%) | 63 | 67 | 60c |
| Non-Caucasian race (%) | 8 | 9 | 7 |
| Primary kidney disease (%) | |||
| Glomerulonephritis | 13 | 10 | 15 |
| Diabetes Mellitus | 15 | 18 | 14 |
| Renal vascular disease | 19 | 18 | 18 |
| Other | 53 | 53 | 53 |
| Educational level (%) | |||
| Level 1 | 5 | 5 | 6 |
| Level 2 | 9 | 9 | 9 |
| Level 3 | 18 | 19 | 17 |
| Level 4 | 42 | 43 | 42 |
| Level 5 | 26 | 25 | 26 |
| Smoking (%) | 27 | 32 | 24b |
| Anthropometry | |||
| Body mass index (kg/m2) | 24.8 (22.5−27.9) | 23.6 (21.5−26.1) | 25.7a (23.3−28.7) |
| Length (cm) | 171.3 ± 9.7 | 171.4 ± 9.3 | 171.3 ± 9.9 |
| Weight (kg) | 74.0 (65−84) | 70.7 (62−79) | 76.9a (67−87) |
| Comorbidities (%) | |||
| Myocardial infarction | 13 | 15 | 12 |
| Heart failure | 12 | 15 | 10c |
| DM | 23 | 26 | 22 |
| Peripheral vascular disease | 16 | 18 | 14 |
| CVA | 10 | 9 | 9 |
| Malignancy | 9 | 10 | 9 |
| Chronic lung disease | 7 | 9 | 6 |
| Charlson Comorbidity Index | |||
| Class 1 | 32 | 34 | 33 |
| Class 2 | 32 | 30 | 32 |
| Class 3 | 36 | 36 | 35 |
| Laboratory results | |||
| eGFR (ml/min/1.73 m2) | 8.0 (5.8−11.4) | 7.1 (5.5−10.0) | 8.3a (6.1−12.5) |
| GFR (ml/min) | 9.5 (7.3−12.3) | 7.4 (5.6−9.2) | 11.2a (8.9−14.0) |
| Hemoglobin (mmol/L) | 6.8 ± 1.1 | 6.5 ± 1.1 | 7.0 ± 1.2a |
| Albumin (g/L) | 38 (34−42) | 36 (31−40) | 39a (35−43) |
| PTH (pmol/L) | 17.8 (10−28.1) | 18.3 (8.3−46.9) | 16.9 (10.0−27.1) |
| SGA total score (%) | |||
| 1−5 = severe to moderate PEW | 9 | 17 | 9 |
| 6−7 = normal nutritional status | 91 | 83 | 92 |
CVA, cerebrovascular accident; DM, diabetes mellitus; GFR, glomerular filtration rate; PEW, protein-energy wasting; PTH, parathyroid hormone; SGA, subjective global assessment of nutritional status; UCrE, urinary creatinine excretion.
Data are given as mean ± SD or median (interquartile range).
Charlson Comorbidity Index: class 3 indicating the highest comorbidity burden.
Educational level: level 1 = university, level 5 = primary school or less.
a
P < 0.001; bP < 0.01; cP < 0.05, cases versus noncases.