Table 2.
Outcome parameters at various time points
15 mo |
18 mo |
21 mo |
24 mo |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
TAC/GCs (n = 35) |
cCTX/GCs (n = 35) |
P value | TAC/GCs (n = 35) |
cCTX/GCs (n = 35) |
P value | TAC/GCs (n = 35) |
cCTX/GCs (n = 35) |
P value | TAC/GCs (n = 35) |
cCTX/GCs (n = 35) |
P value | |
Proteinuria (g/d) | 2.23 ± 3.59 (1.00–3.47) | 1.10 ± 1.18 (0.70–1.51) | 0.08 | 2.00 ± 3.50 (0.80–3.20) | 1.00 ± 1.12 (0.61–1.38) | 0.11 | 2.30 ± 3.53 (1.08–3.51) | 1.04 ± 1.44 (0.54–1.54) | 0.05 | 2.40 ± 3.51 (1.19–3.61) | 1.27 ± 1.67 (0.69–1.84) | 0.08 |
Serum albumin (g/dl) | 3.48 ± 0.97 (3.15–3.81) | 3.93 ± 0.54 (3.74–4.12) | 0.02 | 3.51 ± 0.90 (3.20–3.82) | 3.97 ± 0.62 (3.76–4.19) | 0.01 | 3.48 ± 0.84 (3.18–3.77) | 3.97 ± 0.56 (3.78–4.17) | 0.005 | 3.57 ± 0.89 (3.27–3.88) | 4.00 ± 0.62 (3.79–4.22) | 0.02 |
Serum creatinine (mg/dl) | 0.96 ± 0.18 (0.89–1.02) | 0.93 ± 0.26 (0.84–1.02) | 0.62 | 0.95 ± 0.17 (0.89–1.01) | 0.94 ± 0.23 (0.86–1.02) | 0.78 | 0.91 ± 0.20 (0.84–0.98) | 0.93 ± 0.21 (0.86–1.00) | 0.64 | 0.98 ± 0.25 (0.90–1.07) | 0.92 ± 0.18 (0.86–0.98) | 0.24 |
Values are means ± SDs and 95% confidence intervals.
cCTX, cyclical cyclophosphamide; GCs, glucocorticoids; TAC, tacrolimus.