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Pharmacokinetic parameters (summary statistics) in single-dose study
| Cohort (dosage level) | n | AUClast (ng·h/ml) |
Cmax (ng/ml) |
|---|---|---|---|
| Mean ± SD | |||
| S1 (5 mg) | 4 | 1110 ± 360 | 236 ± 89 |
| S2 (10 mg) | 4 | 2550 ± 110 | 589 ± 88 |
| S3 (20 mg) | 4 | 5460 ± 680 | 999 ± 135 |
AUC last, area under the curve from time 0 to last time point with quantifiable concentration before the next hemodialysis; S, single-dose.
