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. 2017 Nov 8;12(11):e0187732. doi: 10.1371/journal.pone.0187732

Fig 4. Wavelength-selective photostimulation of AMPA and GABA-A receptors in dopamine neurons of the substantia nigra.

Fig 4

(a) Left, summary of inward currents induced by photolysis of dcPNPP-Glu by near-UV and blue light. Solid black line indicates the mean current and the gray area indicates the 95% confidence limits. Right, summary of the increase in inward current induced by longer duration flashes (n = 9 cells). (b) Left, summary of inward currents induced by photolysis of DEAC454-GABA by blue and near-UV light. Right, summary of the increase in current induced by longer pulses of light (n = 9 cells). Recordings were made in the presence of TTX (1 μM), NMDA (CPP, 10 μM), D2 (sulpiride, 2 μM) and GABA-B receptor (CGP-55845a, 500 nM) and mGluR (JNJ-16259685, 1 μM; MPEP, 3 μM) antagonists. For all cells, a single data point was collected at each flash duration and the data were averaged across cells.