Table 2.
CLINICAL AND SEROLOGICAL CHARACTERISTICS OF THE PATIENTS WITH BIOPSY‐PROVEN NAFLD WHO WERE MEASURED FOR BOTH Mac‐2bp AND WFA+‐M2BP
| NAFL | NASH | P Value | |
|---|---|---|---|
| Number | 48 | 68 | |
| Age (y) | 51.8 ± 9.8 | 55.6 ± 12.4 | <0.05 |
| Sex (M/F) | 35/13 | 28/40 | <0.01 |
| BMI (kg/m2) | 26.7 ± 3.9 | 26.9 ± 4.8 | N.S. |
| AST (U/L) | 37.9 ± 26.8 | 64.3 ± 37.0 | <0.0001 |
| ALT (U/L) | 56.2 ± 39.6 | 93.9 ± 60.3 | <0.0005 |
| GGT (U/L) | 104.9 ± 133.4 | 100.7 ± 121.4 | N.S. |
| ALP (U/L) | 244.4 ± 101.8 | 275.3 ± 100.2 | <0.05 |
| CHE (U/L) | 349.7 ± 54.8 | 352.3 ± 71.5 | N.S. |
| T‐Chol (mg/dL) | 208.8 ± 33.2 | 206.4 ± 39.9 | N.S. |
| TG (mg/dL) | 139.0 ± 59.3 | 161.4 ± 92.8 | N.S. |
| HDL‐C (mg/dL) | 51.6 ± 11.5 | 48.9 ± 15.6 | N.S. |
| FBS (mg/dL) | 111.2 ± 22.1 | 103.9 ± 28.2 | <0.05 |
| IRI (mU/mL) | 8.16 ± 3.83 | 14.7 ± 11.2 | <0.05 |
| Albumin (g/dL) | 4.36 ± 0.29 | 4.12 ± 0.35 | <0.0001 |
| Ferritin (ng/mL) | 185.8 ± 148.2 | 375.2 ± 419.8 | 0.07 |
| Platelet count (×104/μL) | 22.6 ± 5.7 | 19.2 ± 5.4 | <0.01 |
| Hyaluronic acid (ng/mL) | 39.6 ± 60.6 | 79.1 ± 109.5 | <0.05 |
| Mac‐2bp (μg/mL) | 1.23 ± 0.56 | 2.05 ± 1.12 | <0.0001 |
| WFA+‐M2BP (COI) | 0.67 ± 0.67 | 1.26 ± 1.10 | <0.0001 |
Abbreviations: CHE, choline esterase; GGT, gamma glutamyltranspeptidase; HDL‐C, high‐density lipoprotein cholesterol; N.D., not determined; N.S., not significant; T‐Chol, total cholesterol; TG, triglyceride.