Figure 4.

Both KCs and IMs in gp91^phox−/− mice show a proinflammatory phenotype after chronic alcohol ingestion. Female WT and gp91^phox−/− mice were treated as described in Fig. 1. After 4 weeks, KCs and IMs were purified by FACS from (A) pair‐fed and (B) EtOH‐fed mice. Expression levels of various proinflammatory, anti‐inflammatory, and tissue reparative genes were compared. *P < 0.05 compared with WT mice. Results shown are from 12 mice per group of three independent experiments. Abbreviation: MRC‐1, mannose receptor C‐type 1. Error bars in the histograms stand for SEM.