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. Author manuscript; available in PMC: 2018 Sep 26.
Published in final edited form as: J Am Coll Cardiol. 2017 Sep 26;70(13):1601–1615. doi: 10.1016/j.jacc.2017.07.789

Figure 6. Effect of TNC Deficiency on AT II-induced Cardiac Hypertrophy.

Figure 6

Figure 6

Figure 6

Figure 6

Infusion with angiotensin (AT) II (A) significantly increased HW-BW ratios but more so in TNCKO mice. As seen via immunostaining (B), AT II infusion also increased collagen deposits in TNCKO compared to WT controls (C). (D) Similar results were seen in fibroblast frequency in peritostin-stained sections of TNCKO and WT hearts. Other abbreviations as in Figures 1 and 5.