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. Author manuscript; available in PMC: 2017 Nov 9.
Published in final edited form as: J Med Chem. 2016 Mar 29;59(7):3112–3128. doi: 10.1021/acs.jmedchem.5b01894

Figure 6.

Figure 6

Illustrations of the in vitro functional pharmacology at the mMC1R, mMC3R, mMC4R, and mMC5R of the Inline graphic based ligands. Top figures show the bivalent ligands compared to the control peptide 1. The bottom figures show the effects of the linkers plus pharmacophore compared to control peptide 1.