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The (a) fundamental, (b) subharmonic, (c) ultraharmonic, and (d) combined-mode CE-IVUS images acquired at 12 MHz transmit frequency. The fundamental and nonlinear CE-IVUS images are displayed at dynamic ranges of 60 dB and 40 dB, respectively to aid visualization. The combined imaging mode achieved higher contrast-to-tissue ratio than standalone use of subharmonic and ultraharmonic imaging modes.
