Table 1.
Nicardipine (n = 926) | Sodium nitroprusside (n = 530) | P-value* | |
---|---|---|---|
Mean age (standard deviation) | 64.6 (14.7) | 64.3 (15.1) | 0.78 |
Sex (men) | 511 (55%) | 278 (52%) | 0.31 |
Risk of mortality | 0.33 | ||
Mild | 38 (4%) | 21 (4%) | |
Moderate | 448 (48%) | 238 (45%) | |
Severe | 165 (18%) | 89 (17%) | |
Extreme | 275 (30%) | 182 (34%) | |
Severity of disease | 0.98 | ||
Mild | 121 (13%) | 67 (13%) | |
Moderate | 288 (31%) | 161 (30%) | |
Severe | 304 (33%) | 177 (33%) | |
Extreme | 213 (23%) | 125 (24%) | |
Labetalol | 288 (31%) | 187 (35%) | 0.10 |
Hospital characteristics | |||
Median number of beds (min–max) | 620 (100–1836) | 442 (60–962) | <0.0001 |
Teaching hospital | 597 (64%) | 302 (57%) | 0.005 |
Urban hospital | 907 (98%) | 472 (89%) | <0.0001 |
Median length of treatment, days (range) | 2 (1–8) | 1 (1–8) | <0.0001 |
Hospital transfer | 62 (7%) | 34 (6%) | 0.84 |
Chi-square for categorical variables, F-test for age, Kruskal-Wallis test for number of beds