Fig. 2.

Effect of mRK35 in mdx mice. a Weekly body weights following intraperitoneal administration of 10 mg/kg/week mRK35 or vehicle (PBS) in 8-week-old male mdx mice. b Forelimb grip strength measured after 8 weeks of treatment. c Tissue wet weights of the TA, gastrocnemius, and quadriceps muscles. d Tissue wet weight of the EDL. e EDL maximum tetanic force from resting length. f EDL cross-sectional area. g EDL specific force. Treatment groups contained 9 (vehicle) or 10 (mRK35) treated mice. Data plotted are means ± SEM. *p < 0.05 versus vehicle as measured by two-tailed Student’s t test