Table 1.
Formulation | Peptide Conc. [mg/mL] |
PFP [vol %] |
Droplet size [nm] | Δ[b] | ζ[c] [mV] |
|
---|---|---|---|---|---|---|
| ||||||
25°C | 37°C | |||||
1.00 | 2 | 1.2 × 103 | 43 × 103 | 36.5 | 3.5 ± 0.2 | |
1.00 | 1 | 863 ± 98 | 23 × 103 | 26.7 | 0.1 ± 0.2 | |
0.75 | 2 | 739 ± 56 | 7.5 × 103 | 10.1 | 6.8 ± 0.5 | |
4[a] | 0.75 | 1 | 469 ± 24 | 482 ± 34 | 1.0 | 8.0 ± 0.4 |
0.50 | 2 | 453 ± 29 | 528 ± 24 | 1.3 | 8.2 ± 0.4 | |
6[a] | 0.25 | 2 | 448 ± 27 | 458 ± 23 | 1.0 | 4.6 ± 0.2 |
0.50 | 1 | 301 ± 14 | 390 ± 12 | 1.3 | 12.4 ± 0.4 |
Formulations 4 and 6 are not colour coded as they are not shown in Fig. 2a due to their similar size to formulation 5.
folds change in particle size at 37°C versus 25°C.
zeta potential