Table 1. Baseline study characteristics by sex and genetic risk score (GRS) tertile (T), Healthy Aging in Neighborhoods of Diversity Across the Lifespan (Mean values with their standard errors).
| Sex | GRStotal tertile | |||||||||||||
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| Total (n 766) | Men (n 343) | Women (n 423) | T1 | T2 | T3 | |||||||||
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| Mean | sem | Mean | sem | Mean | sem | P* | Mean | sem | Mean | sem | Mean | sem | Pfor trend† | |
| Age (years) | 47.4 | 0.6 | 48.4 | 0.8 | 46.6 | 0.8 | 0.14 | 45.7 | 1.1 | 48.2 | 0.7 | 48.8 | 1.2 | 0.043 |
| Marital status (%) | 0.23 | 0.81 | ||||||||||||
| Married | 27.5 | 30.2 | 25.1 | 23.9 | 29.7 | 29.1 | ||||||||
| Missing | 3.6 | 4.8 | 2.5 | 3.7 | 3.7 | 3.0 | ||||||||
| Education (%) | 0.53 | 0.25 | ||||||||||||
| <High school | 3.4 | 2.6 | 4.0 | 3.0 | 3.0 | 4.7 | ||||||||
| High school | 59.6 | 57.3 | 61.7 | 69.0 | 54.0 | 55.0 | ||||||||
| > High school | 37.0 | 40.1 | 34.3 | 28.0 | 43.0 | 40.3 | ||||||||
| Poverty:income ratio<125 %, (%) | 23.5 | 18.6 | 27.9 | 0.015 | 24.8 | 23.6 | 21.6 | 0.83 | ||||||
| Current smoking status (%) | 0.08 | 0.07 | ||||||||||||
| Yes | 48.0 | 56.2 | 40.9 | 55.2 | 39.0 | 52.6 | ||||||||
| Missing | 6.4 | 4.1 | 8.4 | 4.9 | 10.3 | 1.9 | ||||||||
| Current illicit drug use (%) | 0.009 | 0.09 | ||||||||||||
| Yes | 23.6 | 31.8 | 16.3 | 29.5 | 18.6 | 23.0 | ||||||||
| Missing | 4.9 | 2.2 | 7.4 | 1.8 | 8.8 | 3.1 | ||||||||
| BMI (kg/m2) | 29.4 | 0.5 | 27.3 | 0.5 | 31.2 | 0.8 | <0.001 | 28.5 | 0.8 | 30.0 | 0.8 | 29.6 | 1.1 | 0.36 |
| Key dietary intake factors | ||||||||||||||
| Added sugars (teaspoon/d) | 22.6 | 1.2 | 25.3 | 1.7 | 20.2 | 1.6 | 0.031 | 25.9 | 2.2 | 21.2 | 1.8 | 20.0 | 1.6 | 0.029 |
| Alcoholic beverages (drinks/d) | 0.70 | 0.1 | 1.13 | 0.2 | 0.32 | 0.06 | <0.001 | 0.4 | 0.1 | 0.9 | 0.2 | 0.8 | 0.2 | 0.08 |
| Red meat (oz equiv/d) | 1.70 | 0.15 | 2.25 | 0.25 | 1.22 | 0.17 | 0.001 | 2.1 | 0.3 | 1.5 | 0.2 | 1.5 | 0.2 | 0.09 |
| Fish (oz equiv/d) | 1.12 | 0.15 | 1.13 | 0.17 | 1.10 | 0.23 | 0.92 | 1.2 | 0.2 | 1.2 | 0.3 | 0.9 | 0.2 | 0.42 |
| Legumes (cup equiv/d) | 0.04 | 0.01 | 0.06 | 0.02 | 0.02 | 0.06 | 0.034 | 0.02 | 0.01 | 0.06 | 0.02 | 0.04 | 0.01 | 0.13 |
| Dairy products (cups equiv/d) | 0.96 | 0.07 | 1.15 | 0.10 | 0.79 | 0.08 | 0.008 | 1.03 | 0.13 | 0.95 | 0.09 | 0.85 | 0.13 | 0.33 |
| Vitamin C (mg/d) | 83.7 | 5.2 | 99.9 | 8.6 | 69.4 | 5.2 | 0.003 | 79.1 | 7.6 | 89.0 | 8.6 | 81.9 | 11.5 | 0.75 |
| Caffeine (mg/d) | 76.4 | 5.0 | 80.8 | 7.3 | 72.5 | 6.9 | 0.40 | 84.2 | 9.5 | 63.0 | 7.2 | 87.3 | 8.2 | 0.96 |
| Other dietary intake factors | ||||||||||||||
| Total grains (oz equiv/d) | 5.90 | 0.21 | 6.82 | 0.33 | 50.9 | 0.23 | <0.001 | 6.0 | 0.3 | 5.7 | 0.3 | 6.2 | 0.5 | 0.79 |
| Total fruits (cup equiv/d) | 0.77 | 0.05 | 0.93 | 0.08 | 0.62 | 0.06 | 0.003 | 0.7 | 0.1 | 0.8 | 0.1 | 0.9 | 0.1 | 0.40 |
| Total vegetables (cup equiv/d) | 1.39 | 0.10 | 1.54 | 0.19 | 1.25 | 0.07 | 0.15 | 1.3 | 0.1 | 1.5 | 0.2 | 1.3 | 0.1 | 0.62 |
| Other meats (oz equiv/d) | 4.76 | 0.22 | 5.92 | 0.37 | 3.73 | 0.21 | <0.001 | 5.0 | 0.4 | 4.3 | 0.3 | 5.0 | 0.4 | 0.83 |
| Discretionary oil (g/d) | 18.04 | 1.56 | 22.04 | 3.03 | 14.49 | 0.95 | 0.017 | 14.9 | 1.5 | 20.1 | 2.5 | 19.2 | 4.3 | 0.26 |
| Discretionary solid fat (g/d) | 47.45 | 1.96 | 58.26 | 2.84 | 37.87 | 2.37 | <0.001 | 51.7 | 3.6 | 45.6 | 2.9 | 44.3 | 3.5 | 0.13 |
*
P value for null hypothesis of no sex difference based on a design-based F test.
†
Pfor trend value was based on design-based F test for trend in exposures across tertiles of GRS.