Table 3.

Baseline characteristics of study subjects according to sibling history of mitral regurgitation (MR) in the Swedish population.

	No sibling history of MR		Sibling history of MR		P value
	No.	%	No.	%
Population	5,138,298		18,891
Mitral regurgitation	8,389	0.16	239	1.2	<0.001
Valvular surgery	2,233	0.04	83	0.4	<0.001
Sex					0.51
Men	2,627,510	51.1	9,522	50.4
Women	2,510,788	48.9	9,369	49.6
Age at MR diagnosis (years)					0.09
<20	836	10.5	25	10.7
20–29	351	4.4	5	2.1
30–39	673	8.4	11	4.7
40–49	1,509	1.9	41	17.5
50–59	3,038	38.0	100	42.7
60–69	1,579	19.8	52	22.2
Family size					<0.001
Two children	2,433,566	47.4	3,823	20.2
Three children	1,608,473	31.3	5,005	26.5
Four children	629,813	12.2	3,764	20.0
Five or more children	466,446	9.1	6,299	33.3
Chronic Obstructive Pulmonary Disease					0.93
No	4,968,928	96.7	18,007	95.3
Yes	169,370	3.3	884	4.7
Diabetes					0.71
No	4,999,508	97.3	17,741	93.9
Yes	138,790	2.7	1,150	6.1
Obesity					0.15
No	5,081,788	98.9	18,683	98.9
Yes	56,510	1.1	208	1.1
Hypertension					0.12
No	4,873,515	94.8	16,274	86.1
Yes	264,783	5.2	2,617	13.9
Coronary Heart Disease					0.89
No	4,998,073	97.3	17,135	90.7
Yes	140,225	2.7	1,756	9.3