Expression of mRNA for ion channels carrying inward current. In this and similar figures: expression shown in atrial muscle (A; A), transitional tissue (B; TT), inferior nodal extension (C; INE), compact node (D; CN), penetrating bundle (E; PB) and ventricular muscle (F; V) from control (black bars) and PHT (red bars) rats; means (+SEM) shown (n=6-8); bars and asterisks indicate significant differences between control and PHT rats as assessed by the limma test (FDR-corrected P<0.2, i.e. 20%); and, for the control tissues only, letters indicate a significant difference from the appropriately lettered region (lower case letters, FDR-corrected P<0.2, i.e. 20%; upper case letters, FDR-corrected P<0.05, i.e. 5%). Inset, schematic diagram of AV node (from Greener et al.21). CFB, central fibrous body; CS, coronary sinus; IVC, inferior vena cava; FO, fossa ovalis; TV, tricuspid valve.