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Remodelling of AV node predicts heart block in PHT. A, simulated conduction along AV conduction axis under control conditions (top) and in PHT (bottom). Propagation of five consecutive action potentials shown. Membrane potential (colour coded) is shown as a function of time and distance. B, computed conduction velocity (CV) along AV conduction axis under control conditions and in PHT. C, computed action potential profiles along AV conduction axis under control conditions and in PHT.
