Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 9;14:217. doi: 10.1186/s12974-017-0987-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 1 — Characterization of β4 integrin expression on blood vessels in the normal brain. Top panel shows dual-IF on frozen sections of the medulla oblongata from adult mice using antibodies specific for the endothelial marker CD31 (AlexaFluor-488, green) and β4 integrin (Cy3, red). Lower panel shows dual-IF using antibodies specific for smooth muscle cell marker α-SMA (Cy3, red) and β4 integrin (AlexaFluor-488, green). Scale bar = 100 μm. Note that β4 integrin was expressed by only a fraction of CD31-positive vessels, but co-localized strongly with α-SMA