Table 1.
Low-risk definition in classic clinical prediction models. Adapted from Hui et al.8
| Model | Rochester Criteria | Philadelphia Criteria | Boston Criteria |
|---|---|---|---|
|
| |||
| Age (d) | ≤60 | 29–56 | 28–89 |
|
| |||
| Fever definition (°C) | ≥38.0 | ≥38.21 | ≥38.0 |
|
| |||
| History | Gestation ≥37w0d | N/A | No immunizations 48 hours prior to arrival |
| No perinatal antibiotics | No antibiotics 48 hours prior to arrival | ||
| Previously healthy | No dehydration | ||
| Birth hospitalization not longer than mother | Normal vital signs | ||
|
| |||
| Physical Exam | Well-appearing | Well-appearing | Well-appearing |
| No AOM, SSTI, osteomyelitis or septic arthritis | Unremarkable physical exam | No AOM, SSTI, osteomyelitis or septic arthritis | |
|
| |||
| Labs | WBC >5,000 and <15,000/mm3 | WBC <15,000/mm3 I:T ratio < 0.2 | WBC <20,000/mm3 |
| Absolute band count <1500 | UA <10 WBC/hpf | UA <10 WBC/hpf | |
| UA ≤10 WBC/hpf | Negative urine gram stain | CSF WBC <10/mm3 | |
| Stool ≤5 WBC/hpf if diarrhea/bloody stools | CSF WBC <8/mm3 | Negative CXR if respiratory symptoms | |
| Negative CSF gram stain | |||
| Stool with minimal WBC and 0 RBC/hpf if diarrhea/bloody stools | |||
| Negative CXR if respiratory symptoms | |||
1
≥38.0 used in subsequent studies and in clinical practice
Abbreviations: AOM, acute otitis media; SSTI, skin and soft tissue infection; WBC, white blood cell; UA, urinalysis; I:T, immature(bands):total neutrophil; CXR, chest X-Ray