Table 2.

PLASMA BIOMARKER LEVELS AND NASH DIAGNOSIS

		Total	Not/Borderline NASH (n = 162)	Definite NASH (n = 73)
	n	Mean ± SD	Mean ± SD	Mean ± SD	P
Adiponectin (μg/mL)	233	13.1 ± 7.48	13.20 ± 7.26	13.00 ± 7.98	0.92
aPAI1 (ng/mL)	233	54.97 ± 43.96	50.46 ± 45.09	64.87 ± 39.93	0.02
FGF2 (pg/mL)	232	98.6 ± 141.3	93.8 ± 146	109.1 ± 130.9	0.42
Fibrinogen (mg/mL)	234	4.39 ± 2.11	4.44 ± 1.69	4.31 ± 2.84	0.72
Haptoglobin (mg/mL)	235	2.47 ± 1.27	2.48 ± 1.27	2.44 ± 1.28	0.81
IFN‐γ (pg/mL)	218	8.7 ± 21.3	8.3 ± 21.3	9.6 ± 21.5	0.69
IGF‐II (mg/mL)	234	1.83 ± 0.99	1.79 ± 0.99	1.89 ± 1.02	0.48
IL‐1b (pg/mL)	215	0.5 ± 0.8	0.5 ± 0.8	0.6 ± 0.6	0.78
IL‐2 (pg/mL)	226	3.7 ± 8.8	3.6 ± 9.8	4.0 ± 5.8	0.65
IL‐4 (pg/mL)	226	24.8 ± 31.9	24.5 ± 32.5	25.4 ± 30.7	0.84
IL‐5 (pg/mL)	230	1.0 ± 1.8	0.9 ± 1.9	1.1 ± 1.6	0.52
IL‐6 (pg/mL)	235	15.2 ± 91.1	16.7 ± 108.6	12.0 ± 24.0	0.6
IL‐7 (pg/mL)	226	5.0 ± 6.4	5.2 ± 7.4	4.7 ± 3.5	0.47
IL‐8 (pg/mL)	235	3.1 ± 2.0	2.9 ± 2.2	3.4 ± 1.5	0.07
IL‐10 (pg/mL)	234	24.9 ± 99.4	26.1 ± 118.2	22.2 ± 27.5	0.69
MCP‐1 (pg/mL)	235	246.5 ± 100.6	246.9 ± 105.3	245.7 ± 90	0.93
MMP‐9 (ng/mL)	235	63.9 ± 33.3	64.1 ± 35.7	63.4 ± 27.6	0.88
Resistin (ng/mL)	234	14.89 ± 6.32	14.91 ± 6.49	14.87 ± 5.97	0.97
sFasL (pg/mL)	227	107.6 ± 71.4	110.2 ± 78.8	102.1 ± 51.1	0.36
sIL‐1RI (pg/mL)	235	33.8 ± 23.0	32.2 ± 23.8	37.2 ± 32.4	0.11
sIL‐2Rα (ng/mL)	235	0.79 ± 0.36	0.79 ± 0.34	0.79 ± 0.41	0.91
sIL‐6R (ng/mL)	235	21.24 ± 5.39	21.33 ± 5.37	21.04 ± 5.49	0.71
TGF‐β1 (ng/mL)	235	6.86 ± 7.61	7.11 ± 8.63	6.28 ± 4.59	0.34
TGF‐β2 (pg/mL)	223	359.6 ± 343.1	377.9 ± 401.1	321.2 ± 161.2	0.13
TNF‐α (pg/mL)	235	8.4 ± 8.8	7.6 ± 5.0	10.1 ± 13.9	0.13
tPAI1 (ng/mL)	235	45.8 ± 24.8	43.2 ± 24.3	51.4 ± 25.1	0.02
VEGF (pg/mL)	235	551.3 ± 1083.4	473.9 ± 981.7	723 ± 1271.3	0.14

Abbreviations: FGF2, fibroblast growth factor 2; IFN‐γ, interferon gamma; MCP‐1, monocyte chemoattractant protein‐1; sFasL, soluble Fas ligand.