Table 4.
The distribution of the proportion of responders stratified according to age
| Recombinant antigen | Responders | Age category (years) | Total n (%) | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|---|---|
| < 5 n (%) | 5–9 n (%) | ≥ 10 n (%) | χ2 | p value | χ2 | p value | |||
| AMA-1 | Positive | 85 (29.1) | 94 (46.1) | 63 (59.4) | 242 (50.5) | 34.185 | < 0.0001 | ||
| Negative | 207 (70.9) | 110 (53.9) | 43 (40.6) | 360 (49.5) | |||||
| Total | 292 | 204 | 106 | 602 | |||||
| MSP-1 | Positive | 160 (54.8) | 117 (57.4) | 75 (70.8) | 352 (58.5) | 8.317 | 0.016 | ||
| Negative | 132 (45.2) | 87 (42.6) | 31 (29.2) | 250 (41.5) | |||||
| Total | 292 | 204 | 106 | 602 | |||||
| Overall | Positive | 194 (66.4) | 153 (75.0) | 87 (82.1) | 434 (72.1) | 10.748 | 0.005 | 7.567a | 0.009 |
| Negative | 98 (33.6) | 51 (25.0) | 19 (17.9) | 168 (27.9) | |||||
| Total | 292 | 204 | 106 | 602 | |||||
aChi square values obtained from the likelihood ratio tests adjusted for gender and study site