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. 2017 Oct 30;13(10):e1007054. doi: 10.1371/journal.pgen.1007054

Fig 6. Conditional knockdown in neurons identifies important genes for memory formation.

Fig 6

Gal4-Switch system expresses inactive Gal4 transcription factor, resulting in no RNAi hairpin (A). When flies are fed RU486, the Gal4-switch becomes active and can bind DNA, driving RNAi expression (B). Acute wasp exposure experiment shows that flies have ethanol seeking behavior when fed vehicle (C) or RU486 (D). All genotypes maintain ethanol seeking following wasp exposure when treated with vehicle only (E). Ethanol seeking in the memory assay is disrupted for flies expressing RNAi to a subset of genes (F). Error bars indicate bootstrap 95% confidence intervals.