Table 2.
Univariate and multivariate analyses of overall survival using the Cox proportional hazard model
| Variables | Univariate analysis
|
Multivariate analysis
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P-value | HR | 95% CI | P-value | |
| Gender (male vs female) | 1.18 | 0.79–1.75 | 0.401 | |||
| Age (<17 vs ≥17 years) | 1.27 | 0.86–1.87 | 0.227 | |||
| Pathological fracture (yes vs no) | 1.29 | 0.67–2.48 | 0.463 | |||
| Tumor site (extremities vs nonextremities) | 1.86 | 1.06–3.27 | 0.031 | 1.63 | 0.92–2.88 | 0.094 |
| Metastasis | 2.74 | 1.75–4.29 | <0.001 | 1.99 | 1.23–3.22 | 0.005 |
| Neoadjuvant chemotherapy (no vs yes) | 1.40 | 0.87–2.24 | 0.162 | |||
| PLR (≥118 vs <118) | 1.76 | 1.13–2.75 | 0.012 | |||
| NLR (≥2.65 vs <2.65) | 1.81 | 1.23–2.67 | 0.003 | |||
| GPS (1/2 vs 0) | 1.95 | 1.33–2.87 | 0.001 | |||
| CRP/Alb ratio (≥0.210 vs <0.210) | 2.62 | 1.70–4.03 | <0.001 | 2.21 | 1.40–3.49 | 0.001 |
Abbreviations: CRP/Alb ratio, C-reactive protein to albumin ratio; GPS, Glasgow prognostic score; NLR, neutrophil–lymphocyte ratio; PLR, platelet–lymphocyte ratio.