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. Author manuscript; available in PMC: 2018 Nov 15.
Published in final edited form as: J Immunol. 2017 Oct 6;199(10):3525–3534. doi: 10.4049/jimmunol.1701011

FIGURE 5.

FIGURE 5

BMDMs demonstrate that genes within Bbaa1 intervals of ISRCL3 and ISRCL4 partially regulate the magnitude of the IFN response to B. burgdorferi. qRT-PCR analysis of transcripts in BMDMs from B6, B6.C3-Bbaa1, ISRCL3, ICRCL4, and C3H mice stimulated with live B. burgdorferi for 6 h (n = 3 to 4 per group). Transcript levels for Ifnb, Gbp2, Cxcl10, Iigp, and Tyki were normalized to β-actin. Significance for differences between congenic lines and B6 was determined by 1-way ANOVA followed by Dunnett’s multiple comparison test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.