Table 3. Association mapping of molar shape variation.
The name of each significant region is defined by Mo (molar) and chromosomal location. The SNP with lowest p-value, its position in the genome, and p-value are shown. Effect size is calculated as the percentage of molar shape variation explained by the SNP. *All protein coding genes in the significant regions are shown, except for region Mo.X.2 where only genes relevant to the discussion are included; in total it contains 306 protein-coding genes. **Only this region was associated with more than one SNP. The five significantly associated SNPs spam a 55 Mb region (ChrX:104533418–15959832).
| QTL | Chr | Position | Best SNP | p-value | Effect size | PC axis | Genes* |
|---|---|---|---|---|---|---|---|
| Mo.1 | chr1 | 84306638 | JAX00006079 | 5.11E-07 | 1.1% | PC11 | Pid1, Dner |
| Mo.5 | chr5 | 36723779 | JAX00128837 | 5.79E-07 | 3.2% | PC18 | Psapl1, Tada2b, Ccdc96, Grpel1, Tbc1d14, D5Ertd579e, Sorcs2 |
| Mo.6 | chr6 | 97980057 | JAX00619074 | 2.71E-08 | 2.8% | PC7 | Gm765, Mitf |
| Mo.X.1 | chrX | 92638616 | JAX00715960 | 1.18E-07 | 1.6% | PC16 | Fam123b, Zc4h2, Asb12, Arhgef9 |
| Mo.X.2** | chrX | 104533418 | JAX00183055 | 1.28E-10 | 2.2% | PC7 | Rps6ka3, Dach2, Ap1s2, Itm2a and 301 other genes |