Figure 5.

Aldehyde dehydrogenase (ALDH) activity is reduced in lamina propria mononuclear phagocytes (LP‐MNPs) deficient in CCR6. (a) Flow cytometry scatter plots for ALDH activity in small intestine LP from wild‐type (WT) and CCR6^−/− mice. (b) Graph of the percent of CD103⁺ LP‐dendritic cells (DCs) from WT or CCR6^−/− mice that are positive for ALDH activity. (c and d) IgA and IgG production following co‐culture of splenic B cells from WT mice with small intestine CD103⁺ LP‐MNPs isolated from WT or CCR6^−/− mice. n = 4 mice for each condition, *P < 0·05, ns = not significant. [Colour figure can be viewed at wileyonlinelibrary.com]