Figure 4.

A–B, Distribution of the intrinsic cardiac ganglionated plexuses (GP) in the heart. A, posterior; B, superior. Adapted from Dilsizian and Narula.¹²⁸ C–E, Light photomicrographs of human intrinsic cardiac nerves, ganglia and neurons. C, Network of ganglia and nerves stained with methylene blue and dissected from the posteromedial left atrial ganglionated plexus. The ganglia appear as expansions along a nerve (box). D, Enlargement of boxed area in A illustrating a ganglion composed of approximately 150–200 nerve cell bodies. E, High-magnification micrograph of a multipolar neuron. Note the accumulation of lipofuscin granules (arrowheads). Scale bars 52.5mm in C, 250µm in D, 25µm in E. Adapted from Armour et al.²⁵