TABLE 1.
Bivariate and multivariate predictors of completing 6 months of isoniazid preventive therapy (IPT) among 133 patients receiving differentiated HIV care in 5 rural clinics in Eastern Uganda. The multivariate model is restricted to the 119 patients with complete data for age, wealth index, and side effects.
| IPT Completion
|
IPT Completion
|
|
|---|---|---|
| Unadjusted OR (95% CI) p-value |
Adjusted OR (95% CI) p-value |
|
| Female | 0.6 (0.3–1.2) p = 0.133 |
– |
| Married | 1.0 (0.8–1.1) p = 0.625 |
|
| Age | ||
| 15–38 years (ref) |
||
| 39–46 years |
3.5 (2.8–4.3) p = 0.000 |
4.9 (3.8–6.2) p = 0.000 |
| 47 years + |
3.4 (1.3–8.8) p = 0.013 |
4.2 (1.3–13.8) p = 0.019 |
| Any Education (primary education and above) |
1.4 (0.7–3.1) p = 0.354 |
|
| Wealth Index | ||
| Wealth tertile 1 (ref) |
– | – |
| Wealth tertile 2 | 1.2 (0.7–2.1) p = 0.457 |
0.9 (0.3–2.2) p = 0.745 |
| Wealth tertile 3 |
2.0 (1.2–3.3) p = 0.010 |
1.5 (0.7–3.6) p = 0.317 |
| Side effects (in first 2 weeks) |
0.3 (0.1–0.6) p < 0.001 |
0.2 (0.1–0.4) p < 0.001 |
| Pre-IPT HIV viral suppression (HIV RNA<500 copies /ml) |
1.1 (0.1–15.6) p = 0.922 |
IPT= Isoniazid Preventive Therapy; OR= odds ratio; CI= confidence interval
*
Confidence intervals accounted for clustering by clinics and robust standard errors